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John Wayne Casserole

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🤠 John Wayne Casserole Recipe delivers classic comfort food with hearty ground beef, cheese, and biscuit crust for a fulfilling meal.
🥘 This easy-to-make casserole combines savory layers and mild spice, perfect for feeding a crowd with satisfying flavors.

  • Total Time: 1 hour 20 minutes
  • Yield: 10 servings 1x

Ingredients

Scale

2 pounds ground beef, browned and drained

1 packet taco seasoning plus water (amount as directed on the packet)

1 16-ounce can large biscuits

1/2 cup sour cream

1/2 cup mayonnaise

8 ounces cheddar cheese, shredded and divided (half used in the mixture and half for topping)

1 medium onion, halved and sliced (half used in the mixture and half sautéed)

2 medium tomatoes, sliced

1 medium red bell pepper, halved and sliced

4 ounces canned sliced jalapeno peppers

Instructions

1-Getting started: Getting started with John Wayne Casserole is straightforward and fun, with steps that guide you from prep to plate in about 1 hour and 20 minutes. Begin by preheating your oven to 350°F and placing the rack in the center, then grease a 13×9 glass baking dish for even baking.

2-Next: press the biscuits from the 16-ounce can into the dish to form a single layer, joining them and pressing the dough halfway up the sides. Bake this crust on a baking sheet for 12-15 minutes until the edges start to brown lightly, then set it aside while keeping the oven on.

3-While the biscuits bake, brown 2 pounds of ground beef and mix it with 1 packet of taco seasoning and the required water, following the packet instructions. In another bowl, combine 1/2 cup sour cream, 1/2 cup mayonnaise, half of the 8 ounces shredded cheddar cheese, and half of the sliced medium onion.

4-Sauté the remaining half of the sliced medium onion and the sliced medium red bell pepper until slightly tender. Now layer everything in the baked biscuit crust: start with the cooked taco-seasoned ground beef, add 2 sliced medium tomatoes, the sautéed bell pepper and onion mixture, 4 ounces canned sliced jalapeno peppers, the sour cream mixture, and finally the remaining half of the 8 ounces shredded cheddar cheese.

5-Bake uncovered for 30-40 minutes until the cheese melts and the edges are lightly browned. For more ideas on layered dishes, try our Vegan Lasagna Recipe. Plus, check out ground beef safety tips for handling meat properly.

Last Step:

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Notes

🌡️ Use an oven thermometer to ensure correct oven temperature.
⏰ Watch biscuits carefully to achieve light browning without overbaking.
🌶️ The casserole’s jalapenos add mild heat, suitable for those wary of spice.

  • Author: Brandi Oshea
  • Prep Time: 40 minutes
  • Cook Time: 40 minutes
  • Category: Main Dish
  • Method: Baking and sautéing
  • Cuisine: American

Nutrition

  • Serving Size: 1 serving
  • Calories: 607
  • Sugar: 5g
  • Sodium: 940mg
  • Fat: 44g
  • Saturated Fat: 16g
  • Carbohydrates: 28g
  • Fiber: 2g
  • Protein: 25g
  • Cholesterol: 99mg